biological process – Communicable Diseases Research

Identification of the Hub Genes and the Signaling Pathways in Human iPSC-Cardiomyocytes Infected by SARS-CoV-2

Article

Published on 2022-12-012022-11-16
Journal: Biochemical Genetics
[Category] COVID19(2023년), SARS, 유전자 메커니즘,

Genomic variants-driven drug repurposing for tuberculosis by utilizing the established bioinformatic-based approach

Short communication

Published on 2022-12-012022-10-05
Journal: Biochemistry and Biophysics Reports
[Category] 신약개발,

Systematic comparison of ranking aggregation methods for gene lists in experimental results

Article

Published on 2022-10-312022-11-16
Journal: Bioinformatics
[Category] COVID19(2023년), meta-analysis, SARS,

Network analysis for elucidating the mechanisms of Shenfu injection in preventing and treating COVID-19 combined with heart failure

Research article

Published on 2022-09-012022-10-05
Journal: Computers in biology and medicine
[Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘,

[키워드] acting acute respiratory syndrome Analysis approach biological process biological processe caused cell differentiation China Chinese components Compound compound screening coronavirus COVID-19 COVID-19 case Critical cytokine signaling Cytoscape Cytoscape software Diagnosis drug-likeness Effectiveness enrichment analysis Evidence heart failure Hemostasis identify IL-17 immune system indicated Infection Inflammatory response injection involved KEGG pathway Kyoto Lung injury mechanism Medicine National Health Commission network network analysis novel coronavirus disease objective overlapped Pathway analysis Pathway enrichment analysis Pathways patients with COVID-19 pharmacological mechanism Pharmacological mechanisms Pharmacology progression protein-protein interaction regulated Respiratory failure Result SARS-CoV-2 Shenfu injection signaling pathway Stage suggested syndrome System target targets TCM Th17 therapeutic therapy Traditional treat treating COVID-19 Treatment was used
[DOI] 10.1016/j.compbiomed.2022.105845 [Article Type] Research article

Transcriptome Analysis of Peripheral Blood Mononuclear Cells Response in Patients with Severe COVID-19 Reveals Crucial Genes Regulating Protein Ubiquitination

Article

Published on 2022-08-292022-11-16
Journal: Medical science monitor : international medical jo
[Category] 유전자 메커니즘,

[키워드] Analysis analysis ASB16 biological process Cell Characteristics Cluster conducted core gene COVID-19 COVID-19 pandemic DEGs detect differentially expressed gene enrichment evaluate expressed facilitate FBXO11 FOXA1 FOXC1 functional GATA2 gene expression analysis Genes healthy controls hsa-miR-1-3p identify Interaction ITCH macrophages miRNA molecular mononuclear cell Patient performed peripheral Peripheral blood platform progression protein ubiquitination protein-protein interaction regulate Regulating Regulatory response RNA sequencing RNF130 severe COVID-19 signaling pathways single-cell transcription factors Transcriptome TRIM21 UBE2J1 was used were expressed YY1
[DOI] 10.12659/MSM.937532 PMC 바로가기

Joint impact of key air pollutants on COVID-19 severity: prediction based on toxicogenomic data analysis

주요 대기 오염 물질이 COVID-19 심각도에 미치는 공동 영향: 독성 유전체 데이터 분석을 기반으로 한 예측

Article

Published on 2022-07-072022-09-11
Journal: Arhiv za higijenu rada i toksikologiju
[Category] 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Air pollution AML Analysis binding biological process biological processe biological processes carbon monoxide CEBPA citokini Comparative Complication coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 complication COVID-19 complications COVID-19 patient COVID-19 transmission CTD cytokine Cytokine storm Cytokines Data analysis death rate determine disease disease complications Diseases DisGeNET dušikov dioksid English Fever Final GeneMANIA Genes identify IL10 IL1B IL6 in silico indicate Inflammation interactions komplikacije bolesti lebdeće čestice molecular molecular function network nitrogen nitrogen dioxide onečišćivači zraka Other ozon Ozone Particulate Particulate matter pathway Periodic fever physical poremećaj funkcije gena researcher resulting SARS-CoV-2 severe acute respiratory syndrome Coronavirus severity sulphur dioxide sumporov dioksid syndrome the cytokine storm TNF TNFRSF1A ugljikov monoksid.
[DOI] 10.2478/aiht-2022-73-3631 PMC 바로가기 [Article Type] Article

Bioinformatics approach to identify common gene signatures of patients with coronavirus 2019 and lung adenocarcinoma

코로나바이러스 2019 및 폐 선암종 환자의 공통 유전자 서명을 식별하기 위한 생물정보학 접근법

Article

Published on 2022-03-012022-09-11
Journal: Environmental science and pollution research inter
[Category] MERS, 바이오마커, 유전자 메커니즘, 진단,

[키워드] approach association bioinformatics biological process cells cellular component co-expressed commonality Coronavirus 2019 coronavirus disease Coronavirus disease 2019 correlation COVID-19 database dataset DEGs develop differentially expressed gene Differentially expressed genes Diseases enrichment analysis evaluate expressed Gene Expression Gene regulatory networks gene signature global pandemic Healthcare systems hub gene hub genes identify immune immune infiltration infected with COVID-19 lung adenocarcinoma lung cancer management Methylation molecular organs pathological mechanism Pathways Patient patients with COVID-19 platform PPI protein-protein interaction Regulatory reveal SARS-CoV-2 SARS-CoV-2. severe disease significantly Spearman transcription factor treating Treatment was obtained were used with COVID-19
[DOI] 10.1007/s11356-021-17321-9 PMC 바로가기 [Article Type] Article

Exploration of the Mechanism of Lianhua Qingwen in Treating Influenza Virus Pneumonia and New Coronavirus Pneumonia with the Concept of “Different Diseases with the Same Treatment” Based on Network Pharmacology

Research Article

Published on 2022-02-082022-10-31
Journal: Evidence-based Complementary and Alternative Medicine : eCAM
[Category] COVID-19,

[키워드] 3CL ACE2 angiotensin-converting enzyme 2 Apoptosis binding biological process biological processes cell proliferation component components concept COX2 cytokine Cytoscape database DAVID docking docking result emodin enrichment analysis exploration FIVE IL-17 IL-6 immune system Influenza virus interleukin-6 Intervention Invasion involved KEGG Kyoto Luteolin MAPK mechanism metabolism Necrosis network New Novel coronavirus Occurrence Ontology pathway Pathway enrichment analysis Pathways Pharmacology Pneumonia protease Protein quercetin Regulation Result rutin screened Seven T cell receptor target targets TNF Toll-like receptor treating Treatment was used
[DOI] 10.1155/2022/5536266 PMC 바로가기 [Article Type] Research Article

Understanding the activating mechanism of the immune system against COVID-19 by Traditional Indian Medicine: Network pharmacology approach

전통 인도 의학에 의한 COVID-19에 대한 면역 체계의 활성화 메커니즘 이해: 네트워크 약리학 접근

Article

Published on 2022-01-012022-09-11
Journal: Advances in protein chemistry and structural biolo
[Category] SARS, 신약개발, 유전자 메커니즘,

[키워드] ACE activating acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alarm Algorithm alternative medicine approach approved betulinic acid biological process cathepsin cathepsin B cathepsin L cellular clinical trials Compound compounds coronavirus 2 COVID-19 COVID-19 infection determine disease DPP4 drug drug design drug target effective EGFR Emergency use enrichment analyses enrichment analysis Evolution functions gene-gene interaction globe HDAC2 identify IL6 immune system Interaction involved JACOM Kabasura kudineer mechanism medication Medicine molecular docking studies Molecular docking study molecular functions Mutation network network pharmacology Nilavembu kudineer pandemic pathway Pathways performed phenyl plant plants Potential treatment predict raising respiratory RIPK1 SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Side effects target targets the SARS-CoV-2 Traditional Traditional Indian Medicine. Transmission transmissions treat treating COVID-19 understanding Vaccine VEGFA Virtual screening was used
[DOI] 10.1016/bs.apcsb.2021.11.007 PMC 바로가기 [Article Type] Article

SARS-CoV-2 Exacerbates Beta-Amyloid Neurotoxicity, Inflammation and Oxidative Stress in Alzheimer’s Disease Patients

SARS-CoV-2는 알츠하이머병 환자의 베타-아밀로이드 신경 독성, 염증 및 산화 스트레스를 악화시킵니다

Article

Published on 2021-12-192022-09-10
Journal: International Journal of Molecular Sciences
[Category] SARS, 유전자 메커니즘,

[키워드] activated acute respiratory syndrome acute respiratory syndrome coronavirus Alzheimer’s disease Alzheimer’s disease beta-amyloid biological process Brain can not Cell cell cycle clearance Cohort collected Comorbidity coronavirus coronavirus disease COVID-19 COVID-19 cohort deaths Dementia deregulated died Gene Expression Omnibus Health higher risk immune response individuals Inflammation interactome neurotoxicity Next-generation sequencing Ontology oxidative stress pandemic Patient profile Repository respiratory reveal SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Transcriptome transcriptomic triggered Viral viral replication
[DOI] 10.3390/ijms222413603 PMC 바로가기 [Article Type] Article